When asked about an analogy to explain the role of dopamine in my brain and in those who have Parkinson’s Disease, I have thought of this little story:

There is a town called “Normalton” where public transportation flourishes (as well as a great economy).  In Normalton, the taxis run on time and the streets are in good repair.  The factories are in good shape and everything about the economy goes pretty smoothly. In contrast, in the nearby town of “Parkieville”, things are not so great.

In the town of Parkieville, the citizens also rely on the public transportation system; however, there are only a few taxis these days – and the few taxis that are there are in bad shape. The roads and highways are full of potholes and the roads/highways around the town are always congested – traffic moves very slowly to the point of sometimes being completely jammed or frozen on the freeways.

The taxi drivers in Parkieville are themselves in bad shape or poor health.  The taxi drivers are overworked from trying to get people to their jobs on time. The taxi drivers must work overtime. These hard working taxi drivers find that they often go home from a hard days work feeling tired and depressed.

Parkieville has tried to recruit new taxi drivers, but it is hard to get good people to come in to the town, due to a natural barrier of a river surrounding the town that is full of dangerous rocks that could destroy anything – other than a good solid boat.

Scientist outside the town developed boats that could cross the river with these vehicles being able to cross into the town for years now, where they can be converted into taxis at the town’s factories.  In some areas, scientist have implemented boats to remove rocks in the water to allow the the boats that can be converted into vehicles to cross into the city easily.

However, the factories in town are themselves in poor shape, and many are closing down.  Because of the poor conditions of the factories, sometimes production fluctuations with periods of descent work and other unpredictable periods of downtime.  Repairmen were brought in to patch the potholes and repair the few taxis that are there to keep them running for as long as possible.

In Parkieville, even the mail delivery and computer internet systems are slow.  People don’t get their paychecks on time and some people lose their motivation – becoming very apathetic. Outsiders (such as those in nearby Normalton) often refer to the town of Parkieville as being a tragedy. Even the town members find that they often get depressed, however, the brave people of Parkieville try to enjoy or at least make the most out of each day (recognizing that the town still may have many good days ahead of it), while they continue to remain optimistic about a potential discovery or solution to the town problems that may come in the future – thanks to the wonderful efforts of volunteers and scientist who work hard on finding options or solutions.

~ Story by Pdude